 Biography-Kabirullah Lutfy-College of Pharmacy
Kabirullah Lutfy - Associate Professor of Pharmaceutical Sciences
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Degree
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Year
obtained
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Institution
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Ph.D.
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1996
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University of California, Irvine
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M. Sci
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1990
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St. John's University
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B. Pharm
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1980
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Kabul University - Kabul, Afghanistan
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Description of Academic/Research Interests:
Using a combination of behavioral and neurochemical approaches, our laboratory is interested in determining the role of the neuropeptide orphanin FQ/nociceptin (OFQ/N) and its receptor, the opioid receptor-like (ORL-1) receptor, in:
(1) Cocaine sensitization
(2) Buprenorphine's actions to alter pain perception and the function of the mesolimbic dopaminergic reward circuitry.
(3) Opioid tolerance
We are also interested in determining the role of endogenous opioid peptides/receptors system in stress-mediated increases in drug use and abuse.
| Selected Publications |
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Khaliq IA, Farasat S, Ackerson L, Lutfy K. Cocaine fails to elevate pallidal glutamate in rats sensitized to cocaine, Pharmacologyonline, 2005, 1, 154-176.
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Lutfy K, Cowan A. Buprenorphine: A unique drug with complex pharmacology. Current Neuropharmacology, 2004, 2, 395-402.
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Narayanan S, Lam H, Carroll FI, Lutfy K. Orphanin FQ/nociceptin suppresses motor activity through an action along the mesoaccumbens axis in rats. Journal of Psychiatry & Neuroscience, 2004, 29, 116-123.
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Lutfy K, Eitan S, Bryant CD, Yang YC, Saliminijad N, Kieffer BL, Takeshima H, Carroll FI, Maidment NT, Evans CJ. Buprenorphine-induced antinociception is mediated by µ-opioid receptors and compromised by concomitant activation of opioid receptor-like receptors. Journal of Neuroscience, 2003, 23, 10331-10337.
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Lutfy K, Khaliq I, Carroll FI, Maidment NT. Orphanin FQ/nociceptin blocks cocaine-induced behavioral sensitization in rats. Psychopharmacology, 2002, 164, 168-176.
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Contact Information
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Office address: 309 E. Second St.
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Pomona, CA 91766
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Main phone: (909) 469-5500
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Fax: (909) 469-5600
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E-mail: klutfy@westernu.edu
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© 2008 Western University of Health Sciences. All Rights Reserved | 309 E. Second St. Pomona, CA 91766-1854 | (909) 623-6116 